Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSSILTDFEPKFLSSDDLLNLYAEYCNGHYCDFKYKQRRLSDGNIQSHLYFKKDHFIHDYNGIETFKRFIAVKAYDVDNITSLALSNLLCEKFNLDILLTIEAMDKERALFFIRERKKRSKDISYQNIEYLEQMVSTDRAQIQKVSLSIMVFANSKKELDKKSIIVYNTLKKEGFSAVLESINMRPIFFSFFPERNFLNSRLRPQTSQNIASLIMFEKYQEGFKENSWGDCPVSVFKNQNGSAHFFNFQAKQGKDKNDNVVGHTMIIGSTGSGKSTFISFLIANLLTKYDMSVVALDRMNGLEIMTDFFEGQYNTANTDGGFYINPFSLKDSEENRQFLANWIKFMLNIDSDNQQDNKA--SQSIDKVIRDTYN--YMGDQKNQINLLEIAKNLGSSEQDFNEILKSQGEKIYFKNFQDCLDFSNSPLSVINMDAFANDKKLMGLIAMYLFHKLFFEAKEHNKPFFYSLMKLKTTLCIL 4DZI Chain:A ((4-394)) ------ALNYRVIDVDNHYYEPLDSFTRHL------DKKFKRRGVQMLSD-GKRTWAVIGDRVNHFIPNPTFDPIIVPGCLDLLFRGEIPDGVDPASLMKVERLADHPEYQ---NRDARIAVMDEQDIETAFMLPTFGCGVEEALK--------HDIEATMASVHAFNLWLDEDWGFDRPDHRIIAAPIVSLADPTRAVEEVDFVLARGAKLVLVRP-----------APVPGLVKPRSLGDRSHDPVWARLAEA------GVPVGFHLSDSGYLHIAAAWGGK--AKDPLDQVLLDDRAIHDTMASMIVHGVFTRHPKLKAVSIENGS-----------YFVHRLIKRLKKAANTQPQYFPEDPVEQLRNNVWIAPYYEDDLPELARVIGVDKILFGSDWPHGEGLASPVSFTAELKG--------------FSESDIRKIMRDNALDLLG---------------------------

General information: TITO was launched using: RESULT: Template: 4DZI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -22650 for 3180 contacts (-7.1/contact) + 2D Compatibility (PS) -38788 + (NN) -23 + (LL) 7536 1D Compatibility (HY) -1200 + (ID) 1900 Total energy: -57025.0 ( -17.93 by residue) QMean score : 0.118

(partial model without unconserved sides chains): PDB file : Tito_4DZI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4DZI-query.scw PDB file : Tito_Scwrl_4DZI.pdb: