Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQIKIKYLDETQTRINKMEQGDWIDLRAAEDVAIKKDEFKLVPLGVAMELPEGYEAHVVPRSSTYKNFGVIQTNSMGVIDESYKGDNDFWFFPAYALRDTKIKKGDRICQFRIMKKMPAVDLIEVDRLGNGDRGGHGSTGTK 2XCD Chain:B ((3-130)) MQIKIKYLDETQTRISKIEQGDWIDLRAAEDVTIKKDEFKLVPLGVAMELPEGYEAHVVPRSSTYKNFGVIQTNSMGVIDESYKGDNDFWFFPAYALRDTEIKKGDRICQFRIMKKMPAVELVEVEHL--------------

General information: TITO was launched using: RESULT: Template: 2XCD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 524 -69333 -132.31 -541.66 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain B : 0.96 3D Compatibility (PKB) : -132.31 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.96 QMean score : 0.454

(partial model without unconserved sides chains): PDB file : Tito_2XCD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XCD-query.scw PDB file : Tito_Scwrl_2XCD.pdb: