Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCS-RRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMG-IGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF 4BTK Chain:A ((51-335)) ---------NYVVKDRWKVLKKIGGG---EIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTG-DVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKD---KEQVGMIKEKYE---HRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE--------------------------------------

General information: TITO was launched using: RESULT: Template: 4BTK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -153131 for 2209 contacts (-69.3/contact) + 2D Compatibility (PS) -29395 + (NN) -9559 + (LL) 2352 1D Compatibility (HY) -23600 + (ID) 4950 Total energy: -218283.0 ( -98.82 by residue) QMean score : 0.420

(partial model without unconserved sides chains): PDB file : Tito_4BTK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4BTK-query.scw PDB file : Tito_Scwrl_4BTK.pdb: