Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNK----LFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQ-----KAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN 2IZR Chain:A ((4-302)) ---------VLMVGPNFRVGKKIGC-NFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLI--GRPGNKTQQVIHIIDFALAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDW-IGKQLPTPV----------------------------------

General information: TITO was launched using: RESULT: Template: 2IZR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -129443 for 2239 contacts (-57.8/contact) + 2D Compatibility (PS) -30834 + (NN) -10049 + (LL) 1420 1D Compatibility (HY) -29600 + (ID) 7950 Total energy: -206456.0 ( -92.21 by residue) QMean score : 0.500

(partial model without unconserved sides chains): PDB file : Tito_2IZR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IZR-query.scw PDB file : Tito_Scwrl_2IZR.pdb: