Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSTLLEVNNLKTYFFRKKEPIPAVDGVDFHISKGETVALVGESGSGKS-ITSLSIMGLVQSSGGKIMDGSIKLEDKDLTSFTENDYCKIRGNEVSMIFQEPMTSLNPVLTIGEQITEVLIYHKNMKKKEARQRAVELLQMVGFSRAEQIMKEYPHRLSGGMRQRVMIAIALSCNPKLLIADEPTTALDVTIQAQVLELMKDLCQKFNTSILLITHDLGVVSEAADRVIVMYCGQVVENATVDDLFLEPLHPYTEGLLTSIPVIDGEIDKLNAIKGSVPTPDNLPPGCRFAPRCPKAMDKCWTNQPSLLTHKSGRTVRCFLYEEEGAEQS 5DGX Chain:A ((36-248)) -------------------------GVSVDIKAGQTVAFVGKSGSGKTTLTSIISRFYTQHEGEILLDG---VDTRELTLENLRSHLSIVSQNVHL-FDDTVYN-NIAFG---EVSEEEVIDA-LKRANAYEFVQELSDGINTN-----IGNNGSKLSGGQRQRISIARALLKNAPVLIFDE----------------LESLTKSCTT--IVIAHRLSTV-ENADKIVVMDGGRVVESGKHQEL-LEQGGLYT----------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5DGX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 907 -91404 -100.78 -473.60 target 2D structure prediction score : 0.42 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -100.78 2D Compatibility (Sec. Struct. Predict.) : 0.42 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.349

(partial model without unconserved sides chains): PDB file : Tito_5DGX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DGX-query.scw PDB file : Tito_Scwrl_5DGX.pdb: