Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MANTGSLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSGELIAEHDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSQFSQDA--DPRY----ADIGGGPLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGNSLRALVKHLDQMSDDEIVGLNIPTGIPLRYDLDSAMRPLVRGGTYLDPEAAAAGAAAVAGQGRG 2H52 Chain:A ((5-253)) -----KLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVLNRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYNVTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRGKTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGK-

General information: TITO was launched using: RESULT: Template: 2H52.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -98925 for 2015 contacts (-49.1/contact) + 2D Compatibility (PS) -26654 + (NN) -16138 + (LL) -20 1D Compatibility (HY) -17600 + (ID) 5300 Total energy: -164637.0 ( -81.71 by residue) QMean score : 0.414

(partial model without unconserved sides chains): PDB file : Tito_2H52.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2H52-query.scw PDB file : Tito_Scwrl_2H52.pdb: