Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLTEQPNWLMQRAQLTPERIALIYEDQTVTFAELFAASKRMAEQLAAHSVRKGDTAAILLQNRAEMVYAVHACFLLGVKAVLLNTKLSTHERLFQLEDSGSGFLLTDSSFEKKEYE---------HIVQTID----VDELMKEAAEEIEIEAYMQMDATATLMYTSGTTGKPKGVQQTFGNHYFSAV-SSALNLGITEQDRWLIALPLFHISGLSA-LFKSVIYGMTVVLHQR--FSVSDVLHSINRHEVTMISAVQTMLASLLEETNR---CPESIRCILLGGGPAPLPLLEECREK-GFPVFQSYGMTETCSQIVTLSPEFSMEKLGSAGKPLFSCEIKIER-DGQVCEPYEHGEIMVKGPNVMKSYFNRESANEASFQNGWLKTGDLGYLDNEGFLYVLDRRSDLIISGGENIYPAEVESVLLSHPAVAEAGVSGAEDKKWGKVPHAYLVLHKP-----VSAGELTDYCKERLAKYKIPAKFFVLDRLPRNASNKLLRNQLKDARKGELL 4WV3 Chain:A ((13-518)) -----VDILERNLPVRANKTALFTPDREMTFRQVSNEANQVGNALKGLGVRFGECVGLLTLDSAEWVTSFFGIVKLGAIAVGINTLLKPPEYEYILRDCRARVLIVHQEFLPLIESIRGNLPMLEHIVVIG-GYLSFNDWIRP-QPTTLEAAQSHREDICSLNYSSG-TGGPKGIPHAHKDYPLTAQLWGVNVLGLRESDRTFALAKLFFTFGTGGNLIFPWYVGASCVLFPGAARVASNVLSTISRFKPTIFYNAPTGYAAALALKDFSQHDLSSLRLCVSASEALPAALWYAWKEATGVDIIDGIGCTENFHIFISNRPG--DIRPGSSGKPVEGYELKLVDDEGKTVPAGEIGNVLLRSETAALSYWHNFEKSRQTFQGEWLATGDKYFVDADGYYWHAGRSDDMLKVGGIWVSPVEVESTLIQHPAVQECAVIGCPDQSRLIKPKAFIILKPEQIPSEALIRQITDHCTEKMAAYKRPRWIEFVTELPKTATGKIQRFKLRSAAKL---

General information: TITO was launched using: RESULT: Template: 4WV3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2806 -92404 -32.93 -195.36 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -32.93 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.413

(partial model without unconserved sides chains): PDB file : Tito_4WV3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4WV3-query.scw PDB file : Tito_Scwrl_4WV3.pdb: