Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)
Input alignment information:
| Query sequence | MKHLYGLFHYNPMMLGLESLPDPTDTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFIKGVHGKVLFLQKQLAKVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKA---NNQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKFEDNLRCK--YFWRPK-----GVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENKLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCV-AILEKSRLD--HWVLGKTKVFLKYYHVEQLNLLLREVIGRVV-VLQAYTKGWLGARRYKRVREKREKGAIAIQ---SAW---RGYDARRKFKKISNRRNESAAHNQAGDTSNQSSGPHSPVAAGTRGSAEVQDCSEPGDHKVLRGSVHRRSHSQAESNNGRTQTSSNSPAVTEKNGHSQAQSSPKGCDIFAGHANKHSVSGTDLLSSRICHPAPDQQGLSLWGAPQKPGSENGLAQKHRTPRRRCQQPKMLSSPEDTMYYNQLNGTLEYQGSKRKPRKLGQIKVLDGEDEYYKSLSPVDCIPEENNSAHPSFFSSSSKGDSFAQH |
| 3I5F Chain:A ((62-835)) | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KTQETRVVKKDDIGQRNPPKFEMNMDMANLTFLNEASILHNLRSRYESGFIYTYSGLFCIAINPYRRLPIYTQGLVDKYRGKRRAEMPPHLFSIADNAYQYMLQDRENQSMLITGESGAGKTENTKKVIQYFALVAASLAEKKGTLEDQIVQCNPVLEAYGNAKTTRNNNSSRFGKFIRIHFGTQGKIAGADIETYLLEKSRVTYQQSAERNYHIFYQLLSPAFPENIEKILAVPD--PGLYGFINQGTLTVDGIDDEE---EMGLTDTAFDVLGFTDEEKLSMYKCTGCILHLGEMKWKQRGEQAEADGT----AEA-EKVAFLLGVNAGDLLKCLLKPKIKVGTEYVTQGRNKDQVTNSIAALAKSLYDRMFNWLVRRVNQTLD-----TKAKRQFFIGVLDIAGFEIFDFNSFEQLCINYTNERLQQFFNHHMFVLEQEEYKKEGIVWEFIDFGLDLQACIELIEKPMGILSILEEECMFPKASDTSFKNKLYDNHLGKNPMFGKPKPPKAGCAEAHFCLHHYAGSVSYSIAGWLDKNKDPINENVVELLQNSKEPIVKMLFTP----------------------------A--------------------FQTISSVHKESLNKLMKNLYSTHPHFVRCIIPNELKTPGLIDAALVLHQLRCNGVLEGIRICRKGFPNRIIYSEFKQRYSILAPNAVPSGFADGKVVTDKALSALQLDPNEYRLGNTKVFFKAGVLGMLEDMRDERLSKIISMFQAHIRGYLMRKAYKKLQDQR-IGLTLIQRNVRKWLVLRNWEWWRLFNKVKPLL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |
|
General information:
TITO was launched using:
| RESULT:
|
Template: 3I5F.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output
|
3D Compatibility (PKB) -340556 for 5808 contacts (-58.6/contact) +
2D Compatibility (PS) -77593 + (NN) -29008 + (LL) 30012
1D Compatibility (HY) -53200 + (ID) 13050
Total energy: -483395.0 ( -83.23 by residue)
QMean score : 0.376
|
|
|