Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTLLTRIKTETILLESDIKELIDILISPSIGTDIKYELLSSYSEREIQQQELTYIVRSLINTMYPHQPCYEGAMCVCGTGGDKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSGSTDLLNQMNIQTTT-VDDTPNQLNEKDLVFIGATESYPIMKYMQPVRKMIGKPTILNLVGPLINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTEDGEIKNYTLNATDYGLKHAPNSDFKGGSPEENLAISLNILNGKDQSSRRDVVLLNAGLSLYVAEKVDTIAEGIELATTLIDNGEALKKYHQMRGE 1KHD Chain:A ((14-343)) QPILEKLFKSQSMTQEESHQLFAAIVRGELEDSQLAAALISMKMRGERPEEIAGAASALLADAQPFPRPDYDFADIVGTGGDGTNSINISTASAFVAASCGAKVAKHGNR--------CDLLQAFGIRLDMSAEDSRQALDDLNVCFLFAPQYHTGFRHAMPVRQQLKTRTIFNVLGPLINPARPPKALIGVYSPELVLPIAQALKVLGYKNAAVVHG-GGMDEVAIHTPTQVAELN-NGEIESYQLSPQDFGLQSYSLNALQGGTPEENRDILARLLQGKGDAAHARQVAANVALLLKLFGQD-NLRHNAQLALETIRSGTAFERVTALAA-

General information: TITO was launched using: RESULT: Template: 1KHD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -220215 for 2876 contacts (-76.6/contact) + 2D Compatibility (PS) -33959 + (NN) -14141 + (LL) 168 1D Compatibility (HY) -11200 + (ID) 4800 Total energy: -284147.0 ( -98.80 by residue) QMean score : 0.454

(partial model without unconserved sides chains): PDB file : Tito_1KHD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KHD-query.scw PDB file : Tito_Scwrl_1KHD.pdb: