Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNKGQRHIKIREIITSNEIETQDELVDMLKQDGYKVTQATVSRDIKELHLVKVPTNNGSYKYSLPADQRFNPLSKLKRALMDAFVKIDSASHMIVLKTMPGNAQAIGALMDNLD-WDEMMGTICGDDTILIICRTPEDTEGVKNRLLELL 1XXA Chain:A ((4-74)) -------------------------------------------------------------------------------LKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPANGFTVKDLYEAILELF

General information: TITO was launched using: RESULT: Template: 1XXA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 288 -46294 -160.74 -661.34 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -160.74 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.522

(partial model without unconserved sides chains): PDB file : Tito_1XXA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XXA-query.scw PDB file : Tito_Scwrl_1XXA.pdb: