Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLIKLKKIVQIERKPFFITRQKLKLFRIVFNIIFVLMLFYYWSAIPLLLPRLIVVIFLLGSIFLTNKAFIAIKKRIGKTLFIRERLWYILESLKLYDSDGDRILNTAILTFDISNDNAVTISAPLFGDKWTKRLKNLEDNLVAGLGLPLLSKKE-LPNC--VIYQLGHIEE----IEQYVFNNNL-TRKFFQSISSPVIKLSNTQQFSLKSNTNIGVYGRTGTGKTIALQWFLFNALAKGCGTDDSTYLGIVDGKGADLYALGKLLQEELGEQIAIGSSPQMLAKLSREFVDIMNARFEVIKQNSSLNADAYD----------------------LEMTPNFLFVDELASIRDSCGSSKQGKELWNEILQNLGLIARKGRQAGCHLLLSTQDPNAENIPVELRNQISAVLYLGNPGADRLKMAFSMCELENVPTVSDRKGEALFHADGLNSIEPVLTIVPFVDVKTKQDFLQIVRNILPNY 2IUS Chain:A ((863-1237)) ---------------------------------------------------------------------------------QMARLVEARLADFRIKADVVNYSPGPVITRF--------ELNLA-PGVKAAR-ISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGASVGVNAMILSMLYKA--QPEDVRFIMIDPKMLELSVYEGIPHLL----TEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWHPVLKKEPYIVVLVDEFADLMMTVG---------KKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESL----LGMGDMLYSGPNS--TLPVRVHGAFVRDQEVHAVVQDWKAR----

General information: TITO was launched using: RESULT: Template: 2IUS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -144034 for 2902 contacts (-49.6/contact) + 2D Compatibility (PS) -36448 + (NN) -16188 + (LL) 10440 1D Compatibility (HY) -8000 + (ID) 2900 Total energy: -197130.0 ( -67.93 by residue) QMean score : 0.455

(partial model without unconserved sides chains): PDB file : Tito_2IUS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IUS-query.scw PDB file : Tito_Scwrl_2IUS.pdb: