Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTCFLVRDLLPLYLEGDCKRETEHVIEEHLKMCSSCRDMYDTMAEPFELESEQAVEEAYLPEEELRFKQRYYGLLIMKAACWFGAAVAMMLIIKLLI 1OR7 Chain:C ((2-44)) -----QKEQLSALMDGETLDSE---LLNELAHNPEMQKTWESYHLIRDSMR----------------------------------------------

General information: TITO was launched using: RESULT: Template: 1OR7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 80 -14913 -186.41 -346.81 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain C : 0.52 3D Compatibility (PKB) : -186.41 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.52 QMean score : 0.592

(partial model without unconserved sides chains): PDB file : Tito_1OR7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1OR7-query.scw PDB file : Tito_Scwrl_1OR7.pdb: