Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLNSEHFNLIQRALDATANELKELGTDSSPSVISHAQ---TDLEKAVE----HIYSTDHPFLSSHVINRK 3EXI Chain:A ((322-367)) ---------------ASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPF---------

General information: TITO was launched using: RESULT: Template: 3EXI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 9 545 60.50 13.96 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 60.50 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.391

(partial model without unconserved sides chains): PDB file : Tito_3EXI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3EXI-query.scw PDB file : Tito_Scwrl_3EXI.pdb: