Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLLIDIVDETGSVSEEMLKEVENLLQFAAEREGVQDQAEVSVTIVSNDDIHQINKEYRGKDAPTDVISFALEEEGEGEIEIVGAEMPPVLGDIIISADRTREQAEEYNHSFKRELGFLAVHG-FLHLLGYDHMTKEEEEEMFTKQKELLDAYGLKRS 1UUS Chain:A ((595-694)) ---------------------------------------------------QEVNDALQNQDPGTFIIRFSERNPGQFGIAYIGVEMPARIKHYLVQPNDTAAAKKTFPD-------FLSEHSQFVNLLQWTKDTNGAPRFLKLHKDTALGSFAPKRT

General information: TITO was launched using: RESULT: Template: 1UUS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 339 -17003 -50.16 -171.75 target 2D structure prediction score : 0.38 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -50.16 2D Compatibility (Sec. Struct. Predict.) : 0.38 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.305

(partial model without unconserved sides chains): PDB file : Tito_1UUS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1UUS-query.scw PDB file : Tito_Scwrl_1UUS.pdb: