Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAGQPGHMPHGGSSNNLCHTLGPVHPPDPQRHPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIE--DNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDIGYVHQVAKQMHIWMSST 2XK6 Chain:A ((7-262)) -------------------------------------------DYEVLYTIG-----RCQKIRRKSDGKILVWKELDYGSMTEAE-KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHRRS---RDLKPANVFLDGKQNVKLGD-----------------VGTPYYMSPEQMNR---NEKSDIWSLGCLLYELCALMPPFTA--FSQKELAGKIREGKFRRIP-YRYSDELNEIITRMLNLKDYHRPSVEEILENPLILEHHHHHH

General information: TITO was launched using: RESULT: Template: 2XK6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -120734 for 1587 contacts (-76.1/contact) + 2D Compatibility (PS) -23730 + (NN) -14506 + (LL) 1740 1D Compatibility (HY) -20800 + (ID) 4450 Total energy: -182480.0 ( -114.98 by residue) QMean score : 0.577

(partial model without unconserved sides chains): PDB file : Tito_2XK6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XK6-query.scw PDB file : Tito_Scwrl_2XK6.pdb: