Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIE--DNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACTASS 2XK4 Chain:A ((7-262)) --------------------------------DYEVLYTIGT--YGRCQKIRRKSDGKILVWKELDYGSMTEAEKQM-LVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHRRS---RDLKPANVFLDGKQNVKLGDFGL-------------FVGTPYYMSPEQMNRM--NEKSDIWSLGCLLYELCALMPPFTA--FSQKELAGKIREGKFRRIPY-RYSDELNEIITRMLNLKDYHRPSVEEILENPLILEHHHHHH

General information: TITO was launched using: RESULT: Template: 2XK4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -129449 for 1660 contacts (-78.0/contact) + 2D Compatibility (PS) -24915 + (NN) -16040 + (LL) 2000 1D Compatibility (HY) -22800 + (ID) 4400 Total energy: -195604.0 ( -117.83 by residue) QMean score : 0.588

(partial model without unconserved sides chains): PDB file : Tito_2XK4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XK4-query.scw PDB file : Tito_Scwrl_2XK4.pdb: