Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQFHSSSALITPFKKDLSVDEAAYETLIKRQIFQGMDACVPVGTTGESATLTHKEHMRCIEIAIETCKSTKTPSNSRMKVLAGVGSNATSESLSLAKFAQKIGADAILCVSPYYNRPTQQGLFEHYKTIAQSVEIPVMLYDVPSRTGVSIEVPTALKLFREVPNIKAIKEASGSLKRVTEL-HYYEKDFKIFSGEDSLNHSIMFSGGCGVISVTGNLMPNLISQMVNCALKFEYQQALEIQNKLFDLHQALFVETNPIPIKMAMHLAGLIENPSYRLPLVAPSKETIKLLEKTLQQYEVIA 3RK8 Chain:A ((8-291)) -------AIVTPMLKDGGVDWKSLEKLVEWHIEQGTNSIVAVGTTGEASTLSMEEHTQVIKEIIRV-------ANKRIPIIAGTGANSTREAIELTKAAKDLGADAALLVTPYYNKPTQEGLYQHYKAIAEAVELPLILYNVPGRTGVDLSNDTAVRLA-EIPNIVGIKDATGDVPRGKALIDALNGKMAVYSGDDETAWELMLLGADGNISVTANIAPKAMSEVCAVAIAKDEQQAKTLNNKIANLHNILFCESNPIPVKWALHEMGLIDT-GIRLPLTPLAEQYREPLRNALKDAGII-

General information: TITO was launched using: RESULT: Template: 3RK8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -198533 for 2510 contacts (-79.1/contact) + 2D Compatibility (PS) -30725 + (NN) -19343 + (LL) 644 1D Compatibility (HY) -21600 + (ID) 6050 Total energy: -275607.0 ( -109.80 by residue) QMean score : 0.544

(partial model without unconserved sides chains): PDB file : Tito_3RK8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3RK8-query.scw PDB file : Tito_Scwrl_3RK8.pdb: