Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKVYYEDAVKNNALEGKTVAVIGYGSQGHAHSQNLRDNGNNVIIGI-REGKSAESARNDGFDVYSVSEAADKADVIMILLPDETQGETYENEIKPNLKAGNSLVFAHGFNIHFDVINPPSDVDVFLVAPKGPGHLVRRTFVEGGAVPSLFAIYQDATGNARDTALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGATHLIQAGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMEKMRHSISNTAEYGDYVSGPRVVTADTKKAMKEVLTDIQNGNFAKSFINDNKNGFKEFHRMRKEQQGHQIEKVGAELREMMPFVKPQH 4XEH Chain:A ((2-325)) -AKIYKDEDISLEPIKNKTIAILGYGSQGRAWALNLRDSGLNVVVGLERQGDSWRRAIDDGFKPMYTKDAVAIADIIVFLVPDMVQKSLWLNSVKDFMKKGADLVFAHGFNIHFKIIEPPKDSDVYMIAPKSPGPIVRRSYEMGGGVPALVAVYQNVSGEALQKALAIAKGIGCARAGVIESTFKEETETDLFGEQVILVGGIMELIKASFETLVEEGYQPEVAYFETVNELKLIVDLIYEKGLTGMLRAVSDTAKYGGITVGKFIIDKSVRDKMKIVLERIRSGEFAREWIKEYERGMPTVFKELSELEGSTIETVGRKLREMM-------

General information: TITO was launched using: RESULT: Template: 4XEH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -128384 for 2490 contacts (-51.6/contact) + 2D Compatibility (PS) -35651 + (NN) -10681 + (LL) 480 1D Compatibility (HY) -34000 + (ID) 8000 Total energy: -216236.0 ( -86.84 by residue) QMean score : 0.438

(partial model without unconserved sides chains): PDB file : Tito_4XEH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4XEH-query.scw PDB file : Tito_Scwrl_4XEH.pdb: