Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MELIFRIFEMKKTLYITNKLFFANWFVPVIGAVLIQVIGIIVSRRLVVKLLPDDYKFNLYIALLLFVPILASIL-----LFLIYFQKRDFTSLGFTKDNNVLTTISGFITGSLLMFFIYICHWLSGFVEISSSNSFSFGPFFFLFLAYFIQSLTEE----ILFRGYVMTTVTKFKGSFAGVLCNSMLFSFIHFRNYGITAIALFNLFLLGIIFSILFNMTKNILFVTGVHTTWNFTMGCVLGNKVSGGYSPVSLFRITENSSFALWNGGDFGFEGGVLCSLILVGCLAYFSLESVRVSVRY 4Q2E Chain:A ((29-290)) ------ITASVVAPFVVLCFVSYESLIGLVSAILILAGYELIT----LEMKERDARFFYVILLALYPVLYGLVFEEPTQPLSILFITGVVFSLITDKDPSQVFKTVAAFSIALIYVTFFLSFFLPIYRDFGAANALLVLTSTWVFDSFAYFTGLKFGRTRISPRYSPRKSLEGVIGGFLGVVIYTFLYRLVVNDLLSVNVIC----------FRTFLPFAATVAIMDTFGDIFECALKRHYGVKDSGKTLP--------------GHGG----MLDRIDGLLFVAPVSYIVFKILEGVVR-

General information: TITO was launched using: RESULT: Template: 4Q2E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -284809 for 2050 contacts (-138.9/contact) + 2D Compatibility (PS) -24547 + (NN) 4574 + (LL) 3972 1D Compatibility (HY) -19200 + (ID) 2000 Total energy: -322010.0 ( -157.08 by residue) QMean score : 0.164

(partial model without unconserved sides chains): PDB file : Tito_4Q2E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Q2E-query.scw PDB file : Tito_Scwrl_4Q2E.pdb: