Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKQYRVLLYYKYVPIEDPEAFREQHLAFCKELGLLGRILVSSEGINGTVSGTVEQTEKYMETMKADPRFADMVFKIDEAEGHAFKKIFVRHKKELVTLRLEDDVDPNETTGQHLKPAEFYEKMQDPNTIVIDARNDY----------EYDLGHFRGAVRPDIEAFRE----LPEWIEEHKDML---------EGKKILTYCTGGVRCEKFSGWLVKQ-GFEDVAQLDGGIVTYGKDPEVQGKLWDGQCYVFDERISVPVNRVEHVIVGKDYFTGEPCERYVNCANPSCNKKMICTPENEYKYMRSCSHECRTNPRNLYVKEHNMTEEEVNARLAAIETEDHAAAE 1URH Chain:A ((11-130)) -----------------------------------------------------------------------------------------------------------------------LAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAGWQRD-------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1URH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 389 -44210 -113.65 -470.31 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -113.65 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.414

(partial model without unconserved sides chains): PDB file : Tito_1URH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1URH-query.scw PDB file : Tito_Scwrl_1URH.pdb: