Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTVLWVAAVIALACLNVIQFIMKKKRDGNLAYTADQLSYMLSRDSAGQILLPTDDHALKDLLVNINLIVENRQQISAQFAKTEQSMKRMLTNMSHDLKTPLTVILGYIEAIQSDPNMPD-EERERLLGKLRQKTNELIQMINSFFDLAKLESEDKEIPITKVHMNDICKR--NILHYYDAVQSKGFQAAIDIPDTPVYAQANEEALDRILQNLLSNAIQYG---AAGKLIGLTLSYDERNIAITVWDRGKGISETDQQRVFERLYTLEESRNKAFQGSGLGLTITKRLTEKMGGIISVQSKPYERTAFTITLKRMTY 3DGE Chain:A ((23-247)) ----------------------------------------------------------------------------------------FIANISHELRTPLTAIKAYAETIYNSLGELDLSTLKEFLEVIIDQSNHLENLLNELLDFSRLERKSLQINREKVDLCDLVESAVNAIKEFASSHNVNVLFESNVP-CPVEAYIDPTRIRQVLLNLLNNGVKYSKKDAPDKYVKVILDEKDGGVLIIVEDNGIGIPDHAKDRIFEQFYRVDSSLTYEVPGTGLGLAITKEIVELHGGRIWVESEVGKGSRFFVWIPK---

General information: TITO was launched using: RESULT: Template: 3DGE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 906 -105613 -116.57 -482.25 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -116.57 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.418

(partial model without unconserved sides chains): PDB file : Tito_3DGE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3DGE-query.scw PDB file : Tito_Scwrl_3DGE.pdb: