Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAIQLSKGQRIDLTKTNPGLTKAVIGLGWDTNKYSGGHDFDLDASAFLVDAHDNCVNDLDFVFYNNLEHPSGGVIHTGDNRTGEGDGDDEQIIVDFS-KIPAHIEKIGITVTI--------HDAEARSQNFGQVSNAFVRVVDEETQNELLRFDLGEDFSIETAVVVCELYRHGGEWKFNAIGSGFSGGLAALCRNYGLQV 2VO8 Chain:A ((966-1066)) -------------------------GLNGDTEVYSAEYLFEYNAEAFILN-EITSFNDSLFVKSKEVE--PGKVRILVASLGNEIEKDSDLVKVNLTPKISSELEVLGLTTALVGAGDGNTHDLELSSK------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2VO8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 349 -28842 -82.64 -313.49 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -82.64 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.099

(partial model without unconserved sides chains): PDB file : Tito_2VO8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VO8-query.scw PDB file : Tito_Scwrl_2VO8.pdb: