Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKICYVLLSLVCVFLFSGCSAGEEASGKKEDVTLRIAWWGGQPRHDYTTKVIELYEKKNPHVHIEAEFANWDDYWKKLAPMSAAGQLPDVIQMDTAYLAQYGKKNQ-LEDLTPYTKDGTIDVSSIDENMLSGGKIDNKLYGFTLGVNVLSVIANEDLLKKAGVSINQENWTWEDYEKLAYDLQEKAGVYGSNGMHPPDIFFPYYL---------RTKGERFYK-----EDGTGLAYQDDQLFVDYFERQLRLVKAKTSPTPDESAQI---KGMEDDFIVKGKSAITWNYSNQYLGFARLTDSPLSLYLPP----EQMQEKALTLKPSMLFSIPKSSEHKKEAAKFINFFVNNEEANQLIKGERGVPVSDKVADAIKPKLNEEETNIVEYVETASKNISKA-DPPEPVGSA------EVIKLLKDTSDQILYQKVSPEKAAKTFRKKANEILERNN 4JXI Chain:A ((3-406)) ----------------------------SHMEVNLRMSWWGGNGRHQVTLKALEEFHKQHPNINVKAEYTGWDGHLSRLTTQIAGGTEPDVMQTNWNWLPIFSKDGTGFYNL--FSVKEQLDLAQFDPKELQQTTVNGKLNGIPISVTAMIFYFNDATWAKAGLEYPK---TWDELLAAGKVFKEKLG----------DQYYPVVLCAGQTLVLIRSYMTQKYNIPTIDEANKKFAYSPEQ-WVEFFTMYKTMVDNHVMPSTKYYASIVKSSYYEMKPWINGEWAGTYMWNSTITKYSDNLTKPAKLVLGPYPMLPGAKDAGLFFLPAQMLSIGKSTKHPQESAMLINFLLNSKEGVEALGLERGVPLSATAVTQLR------ASGVIKDEDPSVAGLNMALELPHPMTTSPYFLDWQIWSLFLDAIQYIDYGQKTVQETAEYFNKQGDRILKR--

General information: TITO was launched using: RESULT: Template: 4JXI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1875 -136442 -72.77 -363.84 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -72.77 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.433

(partial model without unconserved sides chains): PDB file : Tito_4JXI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4JXI-query.scw PDB file : Tito_Scwrl_4JXI.pdb: