Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKWMCSICCAAVLLAGGAAQAEAVPNEPINWGFKRSVNHQPPDAGKQLNSLIEKYDAFYLGNTKEKTIYLTFDNGYENGYTPKVLDVLKKHRVTGTFFVTGHFVKDQ-PQLIKRMSDEGHIIGNHSFHHPDLTTKTADQIQDELDSVNEEVYKITGKQDNLYLRPPRGVFSEYVLKETKRLGYQTVFWSVAFV------DWKINNQKGKKYAYDHMIKQAHPGAIYLLHTVSRD---NAEALDDAITDLKKQGYTFKSIDDLMFEKEMRLPSL 2C79 Chain:A ((5-188)) -----------------------------------------------------------------KLVALTFDDGPDNVLTARVLDKLDKYNVKATFMVVGQRVNDSTAAIIRRMVNSGHEIGNHSWSYSGMANMSPDQIRKSIADTNAVIQKYAGTTPK-FFRPPN--------LETSPTLFNNV--DLVFVGGLTANDWIPSTTAEQRAA--AVINGVRDGTIILLHDVQPEPHPTPEALDIIIPTLKSRGYEFVTLTEL-----------

General information: TITO was launched using: RESULT: Template: 2C79.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 898 -81273 -90.50 -467.08 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -90.50 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.586

(partial model without unconserved sides chains): PDB file : Tito_2C79.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2C79-query.scw PDB file : Tito_Scwrl_2C79.pdb: