Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMMKYEAVIIGGGPVGFMLASELAIAGVGTCVIERLEKPVPHSKALTLHPRTLELLEMRGILERFVSKGSKIPTGHFSMLDTRLDFSGLDTSCPYTLLLPQSKTEKLLEDHARSLGTEVFRGAEALAVTQNGEAVQTIFKDRDGSVRTITSKFAVGADGAGSTVRKQAKIEFPGTDSTVTAALGDVVLLSPPPSGVLSLCTKEGGVMIVPLSPDRYRVVVISPYRTQTPKDVPVTEEELKADLLRICGTDFGLTDPSWMSRFGNAARQAKRYRDGRIFLAGDAAHIHFPAGGQGLNVGLQDAMNLGWKLAAAIKGSAPSWLLDSYHDERHPAAEGLLRNTEAQTKLIDFTQAGLHLRSMMSELLAFPDVNRYVAGQISALDVRYEADRTMPPNRLNGARLPDMKLILSDGNSERLYSFLQNGTFVLLS------LRQEADDHIEVKGLRTVTASLAEPNEKLRNVHTILIRPDGHVAWAVDASAPDCSEVIQKGISRWFSVTSRV 2QA1 Chain:A ((15-494)) -------IVVGAGPAGMMLAGELRLAGVEVVVLERLVERTGESRGLGFTARTMEVFDQRGILPRFGEVETST-QGHFGGLP--IDFGVLEGAWQAAKTVPQSVTETHLEQWATGLGADIRRGHEVLSLTDDGAGVTVEVRGPEGK-HTLRAAYLVGCDGGRSSVRKAAGFDFPGTAATMEMYLADIKGVELQPR-MIGETLPGGMVMVGPLPGGITRIIVCERGTPP-----PPSWHEVADAWKRLTGDDIAHAEPVWVSAFGNATRQVTEYRRGRVILAGDSAHIHLPAGGQGMNTSIQDAVNLGWKLGAVVNGTATEELLDSYHSERHAVGKRLLMNTQAQGLLFLSGPEVQPLRDVLTELIQYGEVARHLAGMVSGLEITYDVGTGSHP--LLGKRMPALELTTATRETSS-TELLHTARGVLLDLADNPRLRARAAAWSDRVDIVTAVPGEVSATSGLRDTTAVLIRPDGHVAWA----APGSHHDLPMALERWF------

General information: TITO was launched using: RESULT: Template: 2QA1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2788 -239098 -85.76 -509.80 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -85.76 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.435

(partial model without unconserved sides chains): PDB file : Tito_2QA1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QA1-query.scw PDB file : Tito_Scwrl_2QA1.pdb: