Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKTMSAITAAAAVTSCFTGFGAASFSAPAKAAAQTNTLSENTNQSAAELVKNLYNTAYKGEMPQQAQGLTINKSTKGDVHAAFGEPERPVGGDNRFD----LYHWNMGQPGYGFSYHKDMTISEIRYFGTGVERQLNLGGVTPEVLQKQLGP-VNRVLTVPFTDEIDYVYDTGRYELHFVIGTDQTADHVNLKAK 4H0A Chain:A ((42-132)) --------------------------------------------------------------------GTWVGKD-IKVLTSKFGQADR--VYPFRDGYKNYVFK-DK-NSYYIVSTKREE-IVSVYATGEKVNVSPLKIGQHSAEIFNHTSINPEPSF-------------------------------------

General information: TITO was launched using: RESULT: Template: 4H0A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 203 -19822 -97.64 -247.77 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : -97.64 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.249

(partial model without unconserved sides chains): PDB file : Tito_4H0A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4H0A-query.scw PDB file : Tito_Scwrl_4H0A.pdb: