Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLTKRLLTIYIMLLGLIAWFPGAAQAEEKQPAVPAVFLMKTIEGEDISIPN-KGQKTILHFWTSWCPPCKKELPQFQSFYDAHPSDSVKLVTVNLVNSEQNQQVVEDFIKANKLTFPIVLDSKGELMKEYHIITIPTSFLLNEKGEIEKTKIGPMTAEQLKEWTEE 3C73 Chain:A ((6-129)) ------------------------------------FVLEDTNGKRIELSDLKGKGVFLNFWGTWCEHCKKEFPYMANQYKHFKSQGVEIVAVNV---GESKIAVHNFMKSYGVNFPVVLDTDRQVLDAYDVSPLPTTFLINPEGKVVKVVTGTMTESMIHDY---

General information: TITO was launched using: RESULT: Template: 3C73.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 543 -83104 -153.05 -675.64 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -153.05 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.633

(partial model without unconserved sides chains): PDB file : Tito_3C73.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3C73-query.scw PDB file : Tito_Scwrl_3C73.pdb: