Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHRLLLLMMLTALGVAGCGQKKPPDPPNRVPEKKVVETSAFGHHVQLVNREGKAVGFIEIKESDDEGLDIHISANSLRPGASLGFHIYEKGSCVRPDFE-------SAGGPFNPLNKEHGFNNPMGHHAGDLPNLEVGADGKVDVIMNAPDTSLKKGSKLNILDEDGSAFIIHEQADDYLTNPS--GNSGARIVCGALLGNNEKQ 4L05 Chain:A ((1-153)) ------------------------------------ESTTVKMYEALPTGPGKEVGTVVISEAPG-GLHFKVNMEKLTPGYH-GFHVHENPSCAPGEKDGKIVPALAAGGHYDPGNTHHHLGPEGDGHMGDLPRLSANADGKVSETVVAP--HLKKLAEIKQ-----RSLMVHVGGDNYSDKPEPLGGGGARFACGVI-------

General information: TITO was launched using: RESULT: Template: 4L05.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 726 3777 5.20 26.23 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : 5.20 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.402

(partial model without unconserved sides chains): PDB file : Tito_4L05.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4L05-query.scw PDB file : Tito_Scwrl_4L05.pdb: