Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKKFLDAIQQLTKELEMLKKDIDSIKEATV--------RIDKDLLEYREEISKVKQDDSVLIMQQHKDN 2GTV Chain:X ((2-49)) ------------IEKLAEIRKKIDEIDNKILKARWPWAEKLIAERNSLAKDVAEIKNQLG----------

General information: TITO was launched using: RESULT: Template: 2GTV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain X - contact count / total energy / energy per contact / energy per residue : 62 3453 55.69 86.33 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain X : 0.69 3D Compatibility (PKB) : 55.69 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.811

(partial model without unconserved sides chains): PDB file : Tito_2GTV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2GTV-query.scw PDB file : Tito_Scwrl_2GTV.pdb: