Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNMDFNLFMNDIVRQARQEITAAGYTELKTAEEVDEALTKKGTTL-VMVNSVCGCAGGIA-RPAAYHSVHYDKRPDQLVTVFAGQDKEA-TARARDYFEGYPPSSPSFAILKDGKIMKMVERHEIEGHEPMAVVAKLQEAFEEYCEEV 2QGV Chain:A ((7-125)) ------------FDALWQRMLARGWTPVS-ESRLDDWLTQAPDGVVLLSSDPKRTPEVSDNPVMIG-ELL-HEFPDY-TWQVAIADLEQSEAIGDRF--G-AFRFPATLVFTGGNYRGVL----NGIHPWAELINLMRGLVE------

General information: TITO was launched using: RESULT: Template: 2QGV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 484 -10915 -22.55 -94.09 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -22.55 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.573

(partial model without unconserved sides chains): PDB file : Tito_2QGV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QGV-query.scw PDB file : Tito_Scwrl_2QGV.pdb: