Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLKKQTVWLLTMLSLVVVLSVYYIMSPESKNAVQMQSEKSASDSGEVATEKAPAKQDTKEKSGTETEKGKEDGTKGTKDSSADKETSAEASEKGTVVTETADDDLFTTYRLDLEDARSKEREELNAIVSSDDATAKEKSEAYDKMTALSEVEGTEKQLETLIKT-QGYEDALVNAE-GD-KINITVKS--DKHSKSKATAIIDLVAKEIK-TMKD-VAVTFEPSK 4OYC Chain:A ((101-176)) -------------------------------------------------------------------------------------------------------------------------------------------------EKARLYSAIEQRLEQSLQTMEGVLSARVHISY--VHLSALAVYERGSPLAHQISDIKRFLKNSFADVDYDNISVVLSE--

General information: TITO was launched using: RESULT: Template: 4OYC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 216 8549 39.58 123.90 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 39.58 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.658

(partial model without unconserved sides chains): PDB file : Tito_4OYC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4OYC-query.scw PDB file : Tito_Scwrl_4OYC.pdb: