Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQQLTFYSYPSCTSCRKTKHWLKAHQIEFNERHLFRETPTREELKYILSLTTEGIDEILATRSQTFKNLNL--NIEEMTVNEVLELLIEKPKLLRRPILVDNKKLV-IGYNPGELLKLSKKKTVHQSA 3FZ4 Chain:A ((5-111)) ----LTFYEYPKCSTCRRAKAELDDLAWDYDAIDIKKNPPAASLIRNWLENSGLELKKFFNTSGQSYRALGLKDKLHQLSLDEAANLLASDGMLIKRPLLVKEGKIVQIGY------------------

General information: TITO was launched using: RESULT: Template: 3FZ4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 418 -27634 -66.11 -265.71 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -66.11 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.595

(partial model without unconserved sides chains): PDB file : Tito_3FZ4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3FZ4-query.scw PDB file : Tito_Scwrl_3FZ4.pdb: