Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTLVIVIHPNLETSVVNKTWMNRLKQEKDITVHDLYGEYPNFIIDVEKEQQLLLDHERIVFQFPMYWYSSPALLKQWEDDVLTHGWAYGTGG----TKLHGKELLLAISLGAQESDYQAGGEYNITISELIRPFQ-VTANYIGMRFLPAFTQYGTLHLSKEDVKNSAERLVDYLKAEH 1ZX1 Chain:A ((70-203)) ------------------------------VETHEAYKQR-SLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIP-FYDSGLLQGKLALLSVTTGGTAEMYTKTG-VNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKG-------------

General information: TITO was launched using: RESULT: Template: 1ZX1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 477 -34991 -73.36 -273.36 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -73.36 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.462

(partial model without unconserved sides chains): PDB file : Tito_1ZX1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ZX1-query.scw PDB file : Tito_Scwrl_1ZX1.pdb: