Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLTKAEALAHTVIYRKNSRFDKVKEKSEELTLIGKGRSAYVFALTE--GGRKMALKVFF----PEYQATAVKEAAIYEKLAGS---AFYPDIYETGDSFILMEYIKGETFYNCLKKGIAISDDMIQQVEEALSDA-----RAAGLNPSDIHLRNLILTETGAVRVIDVARFEQTKTCTQWDDLKSAYHALYKKPIFPKKIPGFWLEIIAFLYKKDWFQKHFAQRKRKYS 3EQC Chain:A ((31-207)) ---------------KDDDFEKISE-------LGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCD--------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3EQC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 433 -12311 -28.43 -93.97 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -28.43 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.511

(partial model without unconserved sides chains): PDB file : Tito_3EQC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3EQC-query.scw PDB file : Tito_Scwrl_3EQC.pdb: