Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTVYHFVGIKGTGMSPLAQILHDNGYTVQGSDIEKFIFTQTALEKRNITILP-FSAENIKPGM-TVIAGNAFPDTHPEIEKAMSEGIPVIRYHKFLGD-YMKKFTSVAVTGAHGKTSTTGLLAHVIQNAK-PTSFLIGD---------------------GTGQGNE----NSEYFVFEACEY-------RRHFLSYQPDYAIMTNIDFDHPDYFSSIDDVFDAFQEMALQVNK--------GIIACGD----------------DEHLPKIHANVPVVYYGTGEENDFQARNIVKSTEGTTFDVFVRNTFYDTFYI--PAYGHHNVLNSLAVIALCHYEEIDSSIIKHALKSFGGVKRRFNE-KQLGDQVLIDDYAHHPTEIKVTIEAARQKYPDREIVAVFQPHTFTRTQQF-LDEFAESLSGADCVYLCDIFGSARENAGKLTIGDLQGKIHNAKLIEEDDTSVLKAHDKAVLIFMGAGDIQKYMRAYENVMA 3HN7 Chain:A ((4-425)) ----HILGICGTFMGSLALLARALGHTVTGSDANIYPPMSTQLEQAGVTIEEGYLIAHLQPAPDLVVVGNAMKRGMDVIEYMLDTGLRYTSGPQFLSEQVLQSRHVIAVAGTHGKTTTTTMLAWILHYAGIDAGFLIGGVPLVNTTDTNLQQVFAHSSYLGTEKDDSDNSVNTGYFVIEADEYDSAFFDKRSKFVHYRPRTAILNNLEFD------DLDAIQTQFHHMVRMIPSTGKIIMPAATISLEDTLAKGVWTPIWRTSVID------------------NSSDWQAELI--SADGSQFTVSFNDNKEATALVNWSMSGLHNVNNALVAIAAAYNIGVSVKTACAALSAFAGIKRRMELIGDVNDILVFDDFAHHPTAITTTLDGAKKKLADRRLWAIIEPRSNTMKMGIHQDSLAQSATLAD---------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3HN7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1947 29263 15.03 87.88 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 15.03 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.461

(partial model without unconserved sides chains): PDB file : Tito_3HN7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3HN7-query.scw PDB file : Tito_Scwrl_3HN7.pdb: