Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVNQGSPQLVSLVDPYVYQTIKKLIGSRFVIQTVRDT-VRGRLIDVKPD-HITIEGAR-----N-----SVCLIRIQHMISVTPDYSERV 1D3B Chain:A ((7-73)) -----------------IKVLHEAEGHIVTCETNTGEVYRGKLIEAEDNMNCQMSNITVTYRDGRVAQLEQVYIRGCKIRFLIL------

General information: TITO was launched using: RESULT: Template: 1D3B.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 181 -2204 -12.17 -40.06 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -12.17 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.709

(partial model without unconserved sides chains): PDB file : Tito_1D3B.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1D3B-query.scw PDB file : Tito_Scwrl_1D3B.pdb: