Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTDLITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVVFFRGQHQLDDAEQLAFAGLLGTP-IGHPAAIALADDAPIITPINSEFGKANRWHTDVTFAANYPAASVLRAVSLPSYGGSTLWANTAAAYAELPEPLKCLTENLWALHTNRYDYVTTKPLTAAQRA-FRQVFEKPDFRTEHPVVRVHPETGERTLLAGDFVRSFVGLDSHESRVLFEVLQRRITMPENTIRWNWAPGDVAIWDNRATQHRAIDDYDDQHRLMHRVTLMGDVPVDVYGQASRVISGAPMEIAG 4Y0E Chain:A ((37-326)) ----ITVEKLGEHIGARVNGIELRGDLSADRVEAIRLALAINKVLVFTEQHHLDDAGQYAFARLLGEPTLPHPTVRSHGTEL-----LNLE-GAANGWHTDVTFVDRIPKASVLRPVTLPSYGGATTWASTVAAYEQLPKPLRSLVDDLWATHTNLYD---------ERRAAYYTEFTSSRYETVHPVVRVHPETGERSLLLGQFVKSFQDLPSAEFASLFQLLQARITKLENTFRWNWRLGDVAIWDNRATQHYGIADFGEQQRELHRVTLAGDVPVDVHGRRSQILLGDASHYSG

General information: TITO was launched using: RESULT: Template: 4Y0E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -104840 for 2286 contacts (-45.9/contact) + 2D Compatibility (PS) -29862 + (NN) -14911 + (LL) 1356 1D Compatibility (HY) -23600 + (ID) 7850 Total energy: -179707.0 ( -78.61 by residue) QMean score : 0.541

(partial model without unconserved sides chains): PDB file : Tito_4Y0E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Y0E-query.scw PDB file : Tito_Scwrl_4Y0E.pdb: