Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFKPFVGVALAALFAVSAVAHAEDAGPVVIKFSHVVSDDTPKGKGALLFKKLAEERLPGKVKVEVYPNSTLFGDADEIEALRANKVQMLATSLSKFEPYTKQLQVFDLPFLFDDLE-ALKRFQKRDKSRELLRSMAKH-GIYGLAYWNNGMKQLSATRELHRPDDAKGLVFRIQPSSVLEAQFAMLGATAKQLSYAETLKAMQAGSVQGTENTWSNLAGQKIDSVQPYITETNHGALSYMLITSSAFWTGIPYQTRTELESIVDEVTLVVNKEAEALNQKEREHLLAAGKSRLVSLSAEEHEAWRNAMKPLWKNYEAQIGSDVLRAAQVVNRKR 2XXK Chain:A ((5-291)) -----------------------------LKFGMNAGTSSNEYKAAEMFAKEVKEKSQGKIEISLYPSSQLGDDRAMLKQLKDGSLDFTFAESARFQLFYPEAAVFALPYVISNYNVAQKALFDTEFGKDLIKKMDKDLGVTLLSQAYNGTRQTTSNRAINSIADMKGLKLRVPDAATNLAYAKYVGASPTPMAFSEVYLALQTNAVDGQENPLAAVQAQKFYEVQKFLAMTNHILNDQLYLVSNETYKELP----EDLQKVVKDAAENAAKYHTKLFVDGEKDLVTFFEKQGVKITHPDLVPFKESMKPYYAEFVKQTG--------------

General information: TITO was launched using: RESULT: Template: 2XXK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -61483 for 2478 contacts (-24.8/contact) + 2D Compatibility (PS) -30325 + (NN) -13142 + (LL) 4448 1D Compatibility (HY) -14000 + (ID) 3300 Total energy: -117802.0 ( -47.54 by residue) QMean score : 0.482

(partial model without unconserved sides chains): PDB file : Tito_2XXK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XXK-query.scw PDB file : Tito_Scwrl_2XXK.pdb: