Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSQEEHNHEELNDQLQVRRDKMNQLRDNGIDPFGARFERTHQSQEVISAYQDLTKEELEEKAIEVTIAGRMMTKRGKG-KAGFAHLQDLEGQIQIYVRKDSVG-DDQYE-IFKSSDLGDLIGVTGKVFKTNVGELSVKATSFELLTKALRPLPDKYHGLKDVEQRYRQRYLDLIVNPDSKHTFITRSKIIQAMRRYLDDHGYLEVETPTMHSIPGGASARPFITHHNALDIPLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYKDIMSLTENLVAHIAQEVLGTT-TIQY-G-----EEQIDLKPEWKRIHMVDAVKEATGVDFWEEVTVEQAREYAKEHEVE----IKDSMTVGHIINEFFEQKIEETLIQPTFIYGHPVEISPLAKKNPEDPRFTDRFELFIVGREHANAFTELNDPIDQRERFEAQLKEREAGNDEAHLMDEDFVEALEYGMPPTGGLGIGIDRLVMLLTNAPSIRDVLLFPQMRQR 4UP7 Chain:A ((11-569)) -----------KQLFLNRCKDVEEYQKAGHNPWPHKFNVSITVPEFIAKYSGLEKSQV--SDDIVSVAGRVLSKRSSSSALMFIDLHDSQTKLQIMLNKSAYENKEDFVSLTKMIYRGDICGFTGHPTRTKTGELSLIPISGMILSPCLHMLPSMHYGLGDQETRFRKRYLDLIVNPESVKNFVLRTKVVKAVRKYLDDKGFLEVETPILNTIPGGATARPFITHHNQLDIQMYMRIAPELYLKELVVGGINRVYEIGRLFRNEGIDQTHNPEFTTCEFYMAYADYNDIMKMTEELLGNMVKDITGGSTKLEIK-FVTEKKMVLDFTAPFKRISYVHALEEKFGEKIPRPLDGPEALTFLKKQAIRFNAICAEPQTTARVMDKLFGDLIEVDLVQPTFVCDQPQLMSPLAKYHRSEPELTERFELFILKREIANAYTELNNPIVQRSNFEQQAKDKAAGDDEAQLVDEVFLDAIEHAFPPTGGWGLGIDRLAMLLADVDNIKEVILFPTMRP-

General information: TITO was launched using: RESULT: Template: 4UP7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -139431 for 3720 contacts (-37.5/contact) + 2D Compatibility (PS) -51587 + (NN) -14131 + (LL) 1036 1D Compatibility (HY) -46000 + (ID) 10600 Total energy: -260713.0 ( -70.08 by residue) QMean score : 0.463

(partial model without unconserved sides chains): PDB file : Tito_4UP7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4UP7-query.scw PDB file : Tito_Scwrl_4UP7.pdb: