Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAVKKVVTHPAEVLETPAETVTVFDKKLKKLLDDMYDTMLEMDGVGLAAPQIGILKRAAVV--EIGDDRGR-IDLVNPEILEKSGE-QTGIEGCLSFPNVYGDVTRADYVKVRAFNRQGKPFILEARGFLARAVQHEMDHLDGVLFTSKISKYYTEDELADMEG 4DR9 Chain:A ((28-179)) ------------VLRQPAKRVSRIDDELRQTIRQMLQTMYSADGIGLAAPQVGINKQLIVIDLEL-----PPLVLINPKIERTAGDLEQCQEGCLSIPGVYLDVERPEIVEVSYKDENGRPQRLVADGLLARCIQHEMDHLNGVLFVDRVENRLELNEALDKKG

General information: TITO was launched using: RESULT: Template: 4DR9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 644 -63634 -98.81 -444.99 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -98.81 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.450

(partial model without unconserved sides chains): PDB file : Tito_4DR9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4DR9-query.scw PDB file : Tito_Scwrl_4DR9.pdb: