Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLDTQQIKEIIPHRYPFLLVDRITEVEEGKRAKGYKNVTANEEFFNGHFPQYPVMPGVLIVEALAQVGAVAMLIKEEN-RGRLAFFAGIDNCRFKKQVKPGDQLHLEVEIIRARGTIGRGK--GVATVDGEVVCEV-ELTFALGE 3AZ9 Chain:R ((11-153)) -IDIEDIKKILPHRYPFLLVDKVIYMQPNKTIIGLKQVSTNEPFFNGHFPQKQIMPGVLQIEALAQLAGILCLKSDDSQKNNLFLFAGVDGVRWKKPVLPGDTLTMQANLISFKSSLGIAKLSGVGYVNGKVVINISEMTFALS-

General information: TITO was launched using: RESULT: Template: 3AZ9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain R - contact count / total energy / energy per contact / energy per residue : 643 -35648 -55.44 -256.46 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain R : 0.85 3D Compatibility (PKB) : -55.44 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.554

(partial model without unconserved sides chains): PDB file : Tito_3AZ9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3AZ9-query.scw PDB file : Tito_Scwrl_3AZ9.pdb: