Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKKMTIASLILMTAGLTACGANDNAMNDTRNNGNTRPIGYYTNENDADRQGDGIDHDGPVSELMEDQNDGNRNTTNVNNRDRVTADDRVPLATDGTYNNTNNRNMNRNAANNGYDN-QENRRL-AAKIANRVKQVKNVNDTQVMVSDDRVVI-----AVKSHRE-FTKSDRDNVVKAARNYANGRDVQVSTDKGLFRKLHKMNNR 2OKU Chain:A ((443-564)) ------------------------------------------------------------------------------------QVVAAIRHITTGTYIARIREEYQQTEVKPELQPMKEALARMTDRAEALIAFVTEQKDQELLDFQARRLVEMTAHAVFGHLLMLAANDDDSFRQSAEVYLRYGQAEQEKIDSYVRAFRPEELT

General information: TITO was launched using: RESULT: Template: 2OKU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 399 33304 83.47 292.14 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 83.47 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.181

(partial model without unconserved sides chains): PDB file : Tito_2OKU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OKU-query.scw PDB file : Tito_Scwrl_2OKU.pdb: