Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKRRKICYCNTALLLMILLAGCTDSKDGEAQQPSNQASAVQTDEKHTEPEESTKIRKDEAEPITESEESATKAANDT-SSAEEKSKEDNVLAAYSSEKIEYARVWLQLGPNQEIDELNVRHIAAGEPINPNDDTSASYPENVTQLAGSRLVDGSVTYHGNGDGTIHVYNVPLRWDSADDIEKGVMREVTESIIKNRKTVYVDTGDDEKIKRLIDIMMIH 1BOW Chain:A ((1-158)) -----------------------------------------RLGEVFVLDEEEIRIIQTEAEGI-----GPENVLNASYSKLKKFIESNNSYGATFSFQ-----------PYTSIDEMTYRHIFTPVLIS-----SITPDMEITTIPKGRYACIAYNF----SPEHYFLNLQKLIKYIADRQLTVVSDVYELIIPIHY--------EYRVEMKIRIL---

General information: TITO was launched using: RESULT: Template: 1BOW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 660 -36311 -55.02 -255.71 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -55.02 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.235

(partial model without unconserved sides chains): PDB file : Tito_1BOW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1BOW-query.scw PDB file : Tito_Scwrl_1BOW.pdb: