Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSEWWKEAVVYQIYPRSFYDANGDGFGDLQGVIQKLDYIKNLGADVIWLSPVFDSPQDDNGYDISDYKNMYEKFGTNEDMFQLIDEVHKRGMKIVMDLVVNHTSDEHAWFAESRKSKDNPYRDYYLWKDPKPDGSE-----PNNWGSIFSGSAWTYDEGTGQYYLHYFSKKQPDLNWENEAVRREVYD-VMRFWMDRGVDGWRMDVIGSISKYTDFPDYETDHSRSYIVGR--YHSNGPRLHEFIQEMNR----EVLSHYDCMTVGEANGSDIEEAKKYTDASRQELNMIFTFEHMDIDKEQNSPNGKWQIKPFDL----IALKKTMTRWQTGLMNVGWNTLYFENHDQPRVISRWGNDR-KLRKECAKAFATVLHGMKGTPFIYQGEEIGMVN-SDMPLEMYDDLEIKNAYRELVVENKTMSE--KEFVKAVMIKGRDHARTPMQWDAGK-HAGFT--AGDPWIPVNSRYQD-INVKESLEDQDSIFFYYQKLIQLRKQYK-IMIYG-DYQLLQENDPQVFSYLREYRGEKLLVVVNLSEEKALFEAPPELIHERWKVLISNYPQERADLKSISLKPYEAVMGISI 3AXI Chain:A ((13-588)) --KWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVVGLPDAPVVDKNSTWQSSDPYTLNGPRIHEFHQEMNQFIRNRVKDGREIMTVGAMQHASDETKRLYTSASRHELSELFNFSHTDVG---TSPLFRYNLVPFELKDWKIALAE-LFRYING--TDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIKEEHGENSEEMKKFLEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGINVEDEIKDPNSVLNFWKEALKFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYNNKTLFAALNFSSDATDFKIPND--DSSFKLEFGNYPKKEVDASSRTLKPWEGRIYIS-

General information: TITO was launched using: RESULT: Template: 3AXI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3186 141847 44.52 257.90 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.82 3D Compatibility (PKB) : 44.52 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.468

(partial model without unconserved sides chains): PDB file : Tito_3AXI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3AXI-query.scw PDB file : Tito_Scwrl_3AXI.pdb: