Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNAVIVDAKRTIFGNQ-NGLLKPFLPEDLAAPIIRCLSRKLEDQ----VDEVILGNATGRGGNLARLSALQAGLPLSVPGMTIDRQCGSGLEAVRYACSLIQAGAGTMYIAGGSESSSQSPFSERARFSPDA-----IGDPDMGIAAEYTAARYSISRSMQDEYALLSHQRSRNAHDEGFYREEVVALGE------LETDEAFLKTRPIEAIIPRAKPVFD--------TSSGTVTAANSSGIADGAAALLVMEEEKAAALGLKPVLRFIGSAVSGIHPNFPPAAPVVAIRQLLHTHDVTPDDIDLFEINEAFAVKICVCSQELGIPFSKINVRGGALALGHPYGASGAALVTRLFYEAKRRPDCQYAVAAIGSGGGIGLALLFEVLA 3SVK Chain:B ((9-405)) --AFIYEAIRTPRGKQKNGSLTEVKPLNLVVGLVDELRRRYPDLDETLISDMILGVV-----DIARTAVLAAGLPETTGGVQLN----SGLEAVNTAAQKVRSGWDDLVLAGGVESM----------WATDPETNYRIGFVPQGIGADLIATLEGFSREDVDAYALRSQQKAAAAWSGGYFAKSVVPVRDQNGLVILDHDEHMRPDTTMEGL-AKLKTAFDLQKYHWVEKINHVHTGGNSSGIVDGAALVLVGSEKAGKSQGLTPRARIVATATS------MLTGPTPATRKVLDRAGLTIDDIDLFELNEAFASVVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDELERR-NARRALITLCIGGGMGVATIIE---

General information: TITO was launched using: RESULT: Template: 3SVK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2207 -204023 -92.44 -614.53 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain B : 0.77 3D Compatibility (PKB) : -92.44 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.485

(partial model without unconserved sides chains): PDB file : Tito_3SVK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3SVK-query.scw PDB file : Tito_Scwrl_3SVK.pdb: