Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKAVTYQGIK-NVVVKDVPDPKIEKSDDMIIKVTSTAICGSDLHLIHGFIP--NMQEDYVIGHEPMGIVEEVGSGVTKLKKGDRVIIPFNIACGECFFCKNQLESQCDQSNDNGEMGAYFGYSGQTGGYPGGQAEYLRVPFANF-THFKIPESCEEPDEKLSVIADAMTTGFWSVDNA--GVKKGDTVIVLGCGPVGLFAQKFCWLKGAKRVIAVDYVNYRLQHAKRTNKVEI-VNFEDHENTGNYLKEITK-GGADVVIDAVGMDGKMSDLEFLASGLKLHGGTMSALVIASQAVRKGGTIQITGVYGGRYNGFPLGDIMQRNVNIRSGQAPVIHYMPYMFELVSTGKIDPGDVVSHVLPLSEAKHGYDIFDSKMDDCIKVVLKP 3JV7 Chain:A ((1-345)) MKAVQYTEIGSEPVVVDIPTPT-PGPGEILLKVTAAGLCHSDIFVMDMPAAQYAYGLPLTLGHEGVGTVAELGEGVTGFGVGDAVAVYGPWGCGACHACARGRENYCTRAAD-------LGITPPGLGSPGSMAEYMIVD--SARHLVPIG-D--LDPVAAAPLTDAGLTPYHAISRVLPLLGPGSTAVVIGVGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREV-GADAAVKSGAG-AADAIR-ELTGGQGATAVFDFVGAQ--------------------STIDTAQQVVAVDGHISVVGIHAGAHAKVGFFMIP-FGASVVTPYWGTRSELMEVVALARAGRLDI---HTETFTLDEGPAAYRRLREGS-IRGRGVVVP

General information: TITO was launched using: RESULT: Template: 3JV7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2041 -44438 -21.77 -131.86 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -21.77 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.451

(partial model without unconserved sides chains): PDB file : Tito_3JV7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3JV7-query.scw PDB file : Tito_Scwrl_3JV7.pdb: