Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYIMKQSGWLELICGSMFSGKSEELIRRVKRATYAKQEVRVFKPVIDNRYSEAAVVSHNGTSMTSYAISSAADIWDHISESTDVVAVDEVQFFDQEIVEVLSSLADKGYRVIAAGLDMDFRGEPFGVVPNIMAIAESVTKLQAVCSVCGSPASRTQRLIDGKPASYDDPVILVGAAESYEARCRHHHEVPGKSKK 1XX6 Chain:A ((2-190)) -YRPKDHGWVEVIVGPMYSGKSEELIRRIRRAKIAKQKIQVFKPE-------EDVVSHMGEKEQAVAIKNSREILKYFEEDTEVIAIDEVQFFDDEIVEIVNKIAESGRRVICAGLDMDFRGKPFGPIPELMAIAEFVDKIQAICVVCGNPATRTQRLINGKPAFYDDPV-----MESYEARCRKCHVVP-----

General information: TITO was launched using: RESULT: Template: 1XX6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 909 -96644 -106.32 -546.01 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.86 3D Compatibility (PKB) : -106.32 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.86 QMean score : 0.446

(partial model without unconserved sides chains): PDB file : Tito_1XX6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XX6-query.scw PDB file : Tito_Scwrl_1XX6.pdb: