Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLP--RGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE 2W17 Chain:A ((7-288)) -----FQKVEKIGE-TYGVVYKARNKLTGEVVALKKIRLD--------VPSTAIREISLLKELN---HPNIVKLLDVIHT-----E-KLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLA------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP

General information: TITO was launched using: RESULT: Template: 2W17.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 3676 for 1971 contacts (1.9/contact) + 2D Compatibility (PS) -26687 + (NN) -3777 + (LL) 964 1D Compatibility (HY) 15200 + (ID) 750 Total energy: -11374.0 ( -5.77 by residue) QMean score : 0.095

(partial model without unconserved sides chains): PDB file : Tito_2W17.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2W17-query.scw PDB file : Tito_Scwrl_2W17.pdb: