Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVTKSEIVISAVKPEQYPEGGLPEIALAGRSNVGKSSFINSLINRKNLARTSSKPGKTQTLNFYII---NDELHFVDVPGYGFAKVSKSEREAWGRMIETYITTREELKAVVQIVDLRHAPSNDDVQMYEFLKYYGIPVIVIATKADKIPKGKW--DKHAKVVRQTLNIDPEDELILFSSETKKGKDEAWGAIKKMINR 1MKY Chain:A ((178-353)) --------------------TDAIKVAIVGRPNVGKSTLFNAILNK-ERALVSPIP------VDDEVFIDGRKYVFVDTAGL----------EKY--SNYRVVDSIEKADVVVIVLDATQGITRQDQRMAGLMERRGRASVVVFNKWDLVVHREKRYDEFTKLFREKLYFIDYSPLIFTSADKGWNIDRMIDAMNLAY--

General information: TITO was launched using: RESULT: Template: 1MKY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 752 -19062 -25.35 -123.78 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -25.35 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.539

(partial model without unconserved sides chains): PDB file : Tito_1MKY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1MKY-query.scw PDB file : Tito_Scwrl_1MKY.pdb: