Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEA-AATDLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDER--RVKLTDFGFGRQAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRG---VLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG 4MXA Chain:A ((29-288)) -----------YKGQRVLGKGSFGEVILCKDKITGQECAVKVISKRQVKQKTDKESLLREVQLLKQLDHPNIMKLYEFFE-DKGYYYLVGEVYTGGELFDEIISRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESKSKDANIRIIDFGLSTHFEASKKMKDK-IGTAYYIAPEVLHG-TYD-EKCDVWSTGVILYILLSGCPPFNGANEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRISARDALDHEWIQTYTKE

General information: TITO was launched using: RESULT: Template: 4MXA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -129318 for 1942 contacts (-66.6/contact) + 2D Compatibility (PS) -27820 + (NN) -17928 + (LL) 776 1D Compatibility (HY) -22400 + (ID) 4150 Total energy: -200840.0 ( -103.42 by residue) QMean score : 0.457

(partial model without unconserved sides chains): PDB file : Tito_4MXA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MXA-query.scw PDB file : Tito_Scwrl_4MXA.pdb: